Introduction to Letybo

In Philadelphia

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Introduction to Letybo

As the latest FDA-approved neuromodulator to enter the U.S. market, Letybo offers patients a new, highly purified solution for smoothing frown lines and rejuvenating the upper face. At our Bryn Mawr and King of Prussia offices, Dr. John Lee and Dr. Joseph Castelli are proud to offer Letybo as part of their commitment to providing advanced aesthetic care backed by proven clinical research. Whether you’re new to wrinkle-relaxing treatments or exploring alternatives to BOTOX or Dysport, Letybo delivers a refined experience with noticeable results.

What is Letybo?

Letybo is a botulinum toxin type A injectable that temporarily reduces the appearance of moderate to severe glabellar lines, or frown lines between the eyebrows. Like other neuromodulators (such as BOTOX), it works by gently blocking nerve signals to targeted facial muscles, preventing repetitive movements that cause deep wrinkles. What sets Letybo apart is its high purity and precision manufacturing process, which minimizes unnecessary proteins and may reduce the risk of developing resistance over time. Letybo is already widely used in international markets and has now become a trusted alternative for patients interested in natural-looking, yet refreshed results.

Women with black hair getting an injectable while sitting up in exam chair. The doctor, wearing blue latex gloves and black scrubs carefully gives the injection. - Liquid Facelift in Bryn Mawr, PA

What’s the First Step?

Your journey with Letybo begins with a one-on-one consultation at our Bryn Mawr or King of Prussia office in the greater Philadelphia area. This is your opportunity to discuss what you hope to achieve, whether softening deep lines or simply maintaining a youthful, rested appearance. Dr. Lee or Dr. Castelli will assess your facial movements, skin condition, and medical history to determine how Letybo can best serve your goals. They will also explain how Letybo compares to other neuromodulators so that you can make a fully informed decision. Once a personalized plan is in place, treatment can often be performed during the same visit, if you’re ready to move forward.

What Are the Benefits of Letybo?

Letybo offers many of the same aesthetic benefits as other neuromodulators, with the added advantage of a clean formulation and consistent performance. Patients often choose Letybo for its:

  • Smoother, younger-looking skin in the forehead and glabellar region
  • Subtle, natural results that don’t freeze facial expression
  • Fast treatment times with minimal to no downtime
  • FDA-approved safety profile, backed by rigorous clinical studies
  • High purity formulation, which may appeal to patients concerned about long-term tolerance or immunogenicity

Who Are the Best Candidates for Letybo?

The best candidates for Letybo are healthy adults who are beginning to notice lines between the eyebrows that don’t fade, even when their face is at rest. These lines (commonly called “frown lines” or “11s”) can make someone appear tired, tense, or older than they really are. Patients who have previously used BOTOX or similar treatments may also find Letybo to be a comfortable and effective switch, particularly if they’re interested in trying a cleaner, more purified formulation. During your consultation, Dr. Lee, Dr. Castelli, or one of our team members will evaluate your goals, facial anatomy, and treatment history to ensure Letybo is the right choice for you.

What to Expect on the Day of Letybo Treatment

Letybo treatments are quick, minimally invasive, and performed right in the comfort of one of our Philadelphia offices. After reviewing your treatment plan and answering any final questions, we will cleanse the area and carefully administer a series of small injections into the muscles that cause glabellar lines. Most patients describe the sensation as a light pinch; the entire process typically takes less than 15 minutes. You’ll be free to return to most normal activities right away, although we may recommend avoiding strenuous exercise or lying down flat for a few hours.

Letybo Recovery

Recovery from Letybo is simple and often barely noticeable. While it’s normal to experience slight redness, swelling, or pinpoint bruising at the injection sites, these effects are typically mild and short-lived; most patients resume social or professional activities the same day. We’ll provide clear aftercare instructions, which may include avoiding rubbing the area or lying flat for several hours post-treatment. Some individuals notice subtle softening within a few days, with full results settling in over one to two weeks. Our team is always available for follow-up questions or to assess your response to treatment, ensuring a smooth and confident experience from start to finish.

How Much Does Letybo Cost in Philadelphia, PA?

Cost for Letybo treatment starts at $10/unit with a $300 minimum when administered by Dr. Castelli and Dr. Laterra, and $12 per unit with a $600 minimum when treated by Dr. Lee. The exact cost of your session will depend on the number of units needed to achieve your desired result, which is something we’ll determine together during your consultation. Compared to other neuromodulators, Letybo offers a cost-effective option with the same high level of precision and aesthetic outcome. We’re happy to walk you through pricing, payment options, and what to expect so that you can plan confidently.

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Why Choose Us?

When it comes to facial aesthetic treatments, expertise matters. Both Dr. John Lee and Dr. Joseph Castelli bring decades of experience in cosmetic facial surgery and non-surgical rejuvenation, backed by prestigious affiliations including the American Academy of Cosmetic Surgery and the American Society of Ophthalmic Plastic and Reconstructive Surgery. Our practice is known throughout the greater Philadelphia area for natural-looking results, meticulous technique, and deeply personalized care. We understand that choosing a new treatment, especially one as new to the U.S. as Letybo, can feel like a big step. That’s why we approach every patient interaction with clarity, respect, and a deep commitment to helping you feel confident in your decision. You’ll never be rushed or upsold at our office—just supported.

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Schedule A Consultation

If you’ve been curious about refreshing your look without changing who you are, Letybo may be the right step forward. We invite you to schedule a consultation at our Bryn Mawr or King of Prussia office, where Dr. Lee or Dr. Castelli will evaluate your concerns, explain the treatment process in detail, and provide expert recommendations tailored to your facial anatomy. Reach out today and take that first step toward a refreshed, confident version of you in the greater Philadelphia area.

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Patient Testimonials

4.9 out of 347+ reviews

  • Dr. Lee is the best. I am so grateful and happy that I got the lower bleph procedure. It wasn’t bad at all. I was anxious at first but the team and Dr. Lee make sure you are relaxed and comfortable. If you have been thinking about doing this procedure- just do it!!!! You will be so happy!!! I am!!

    Melissa Webb

  • Dr. Lee exceeded my expectations with his exceptional skill and compassionate care. From consultation to post-op, he ensured a seamless experience. The results were fantastic reflecting his meticulous attention to detail. I highly recommend Dr. Lee and his wonderful staff!!

    Chris B.

  • Today was my first time getting a facial in Dr. Lee’s office with Juliana, it was so relaxing and my skin is glowing more than it ever has, i am so happy! I definitely recommend coming here for high quality service and high quality products! You will not be disappointed!

    Kristine H.

  • I do thorough research before going to any physician and Dr. Lee came up repeatedly as the most skilled plastic surgeon for the face. I chose him to do my lower blepharoplasty and couldn’t be more pleased. Not only is he skilled but he is kind, humble and concerned about his patients. I would trust Dr. Lee for any plastic surgery procedure I decide to have in the future.

    Jeannette R.

  • I sought out Dr. Lee due to his experience with treatment of TMJ. I was living with daily jaw pain and headaches. A treatment plan was created for me and my quality of life has drastically improved. Due to Dr. Lee’s expertise with facial anatomy, my smile has remained optimal and he has taken care to maintain symmetry in my face. Wonderful practice and team!

    Renee W.

  • Dr. Lee is an expert with an artistic eye. I wouldn’t go to anyone else. He is extremely knowledgeable, talented and very kind. I’m always pleased with the results after seeing him.

    Penelope W.

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